PES Alphamine - Scientific Review

Tuesday, 24 September 2013


Updated: September 24 2013
What Is It?
Alphamine is a fat burner, according to PES it is an extreme thermogenic powder, a muscle hardening agent with fat igniting technology and a powerful stimulant system. 
This is a supplement science review/analysis of Alphamine, not a user review. User reviews can be found be clicking here
You can read more about each of the ingredients by clicking on them.

Ingredients/Contents/Nutritional Information of Alphamine
1. Lean Performance System: Choline Bitartrate, Alpha-Hydroxy-Isocaproic Acid, Eucommia Ulmoides Leaf (98% Chlorogenic Acid), Olea Europaea Leaf (Extracted for Oleuropein)[1]  
2. Ergo-Thermogenic System: Caffeine Anhydrous, Higenamine HCl, Pausinystalia Yohimbe Bark (Extracted for Alkaloid Content) (SA2-A™), N-(2-hydroxy-2-p-methoxyphenylethyl) benzamide, N-Coumaroyldopamine[1]  

Note: Pausinystalia Yohimbe Bark (Extracted for Alkaloid Content) (SA2-A™) is not found in the European version of Alphamine!

PES Alphamine PES Alphamine

Analysis/Review Summery of the Ingredients/Contents

1. Choline Bitartrate: choline supplementation may increase endurance performance, but this increase might only be evident in activities that reduce circulating choline levels below normal. [2]  

2. Alpha-Hydroxy-Isocaproic Acid (HICA): may increase the lean mass, but the effects are small and unreliable. There is also limited evidence of its effects
[3]   

3. Eucommia Ulmoides Leaf (98% Chlorogenic Acid): have some anti-inflammatory properties and may increase steroid signalling
[4]   

4. Olea Europaea Leaf (Extracted for Oleuropein): this is an extract from olive leafs and it may decrease the oxidation of LDL, decrease LDL-C, increase HDL-C, increase insulin sensitivity and benefit the overall glucose metabolism. But it does not significantly effect the weight of humans
[5] 

5. Caffeine Anhydrous: increases anaerobic running capacity, power output, aerobic exercise, fat oxidation, thermogenesis, blood flow
[6] 

6. Higenamine HCl: it has similar mechanisms to ephedrine; but there is limited evidence on this
[7] 

7. Pausinystalia Yohimbe Bark (Extracted for Alkaloid Content) (SA2-A™): notable decrease in fat mass; limited evidence; appears to affect both obese and lean individuals
[8]   

8. N-(2-hydroxy-2-p-methoxyphenylethyl) benzamide (tembamide): it is a beta-agonist that keeps the  stimulant effect last longer; limited evidence
[9]   

9. N-Coumaroyldopamine: is highly selective beta-2 agonist. But this is only in its unmetabolized form; this means that is exceptionally vulnerable to multiple metabolic processes, so it might not be that effective
[10]  

Conclusion
May have comulating effect, so its supplementation might be beneficial as a weight loss aid. 
Verdict: May be added to your supplement stack

Recommended Dosage (Used in the Studies)
According to the product label: begin drinking 1 scoop mixed with 4-5 oz water on an empty stomach 15-30 minutes before breakfast for the first two (2) days to assess tolerance. An additional 1 scoop may be taken 5-6 hours later. Once the above steps have been taken, an additional scoop may be added to the morning serving on day 3. DO NOT EXCEED 3 SCOOPS IN ANY 24 HOUR PERIOD. DO NOT USE PRODUCT FOR LONGER THAN 8 WEEKS FOLLOWED BY A SUBSEQUENT 4 WEEK BREAK. Consume at least 124 Fl. Oz. of liquid per day for men and 91 Fl. Oz. of liquid per day for women while taking this product. Under no circumstances should the initial dose be exceeded or the warnings on this bottle be ignored. [1]  


Where Can You Buy This Supplement?

Amazon.com

Side Effects of This Supplement

Side effects of each of the ingredients/compunds. You can read more about the product on Physique Enhancing Science (PES) site by clicking here

References

1. Pescience - PES Alphamine
2. Muscular Science - Choline
3. Muscular Science - Alpha-Hydroxy-Isocaproic Acid (HICA)
4. Muscular Science - Eucommia Ulmoides
5. Muscular Science - Olive leaf extract (Olea Europaea Leaf Extracted)
6. Muscular Science - Caffeine 
7.Muscular Science - Higenamine 
8. Muscular Science - Yohimbine (Yohimbe Extract)
9. Muscular Science - N-(2-hydroxy-2-p-methoxyphenylethyl) benzamide (tembamide)
10. Muscular Science - N-Coumaroyldopamine

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