Updated: September 25 2013
What Is t?Piceatannol is a stilbenoid and a phenolic compound.
Where Can It Be Found?
Piceatannol is found in roots of Norway spruces (Picea abies), seeds of the palm Aiphanes horrida and in Gnetum cleistostachyum. It is also a metabolite of resveratrol found in red wine.
What Does Animal/Tissue Culture Research Studies Say?
1. Less sore muscles
2. Aid in fighting different diseases by inhibiting protein-tyrosine kinase
3. Piceatannol causes delay or complete inhibition of adipogenesis; this means that it might control obesity, weight gain, and aid in weight loss
4. May promote glucose uptake and decrease blood glucose levels in type 2 diabetes mellitus mice
5. Piceatannol, as a natural product, has anti-colitic effect; might be used against colitis
6. Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb acts as an arginase inhibitor and can boost synthesis of nitirc oxid (NO); might be used for erectile dysfunction (ED) and as a pre-workout
7. Small increase and improvement of vascular function by acute vasorelaxation/vasodilatation due to up-regulating eNOS expression; this was seen in human umbilical vein cells. [7]
Do You Need This Supplement?
More research is needed for a righteous conclusion.
Verdict: Not essential in your supplement stack for muscle growth/weight lossWhere Can You Buy Piceatannol?
For the moment there are no products containing piceatannol.
References
1. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.
2. Piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitor.
3. Piceatannol, Natural Polyphenolic Stilbene, Inhibits Adipogenesis via Modulation of Mitotic Clonal Expansion and Insulin Receptor-dependent Insulin Signaling in Early Phase of Differentiation
4. Piceatannol, a resveratrol derivative, promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and suppresses blood glucose levels in type 2 diabetic model db/db mice.
5. Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1α protein by inhibiting HIF prolyl hydroxylase.
6. Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity.
7. Effect of long-term piceatannol treatment on eNOS levels in cultured endothelial cells.
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