Updated: September 8 2013
What Is It?D-aspartic acid (DAA) is one of the two forms of the amino acid Aspartic Acid; D-aspartic acid and L-aspartic acid (LAA). DAA is associated with some small health benefits, not LAA.
D-Aspartate is a neurotransmitter and a stimulant binding to NMDA receptors, though not as strongly as the amino acid neurotransmitter glutamate does. DAA can turn into N-Methyl-D-Aspartate (NMDA) which is a chemical that causes gonadotropin releasing hormone (GnRH) to be secreted from the hypothalamus.
D-aspartic acid (DAA) is produced naturally in the body but also found in foods (fish, poultry, meat, eggs, dairy, nuts, seeds and legumes). It is produced in the human body from oxaloacetate by transamination. It can also be generated from ornithine and citrulline in the urea cycle.
What Does Research (Human Studies) Say?
1. Increase in testosterone; small and unreliable effect; may be an acute effect (6-12 days). [1-3]
2. Increases fertility; notable effect; but still limited evidence. [3]
3. Increase in sperm quality; small effect. [3]
4. Increase in sperm count; small effect; 50-100% increase over baseline. [3]
5. Increase in seminal motility; small effect; 50-100% increase over baseline. [3]
6. Increase in luteinizing hormone (LH); small and unreliable effect; 30-60% increase in LH. [3]
7. No effect/non-significant effect on lean mass. [2]
8. No effect/non-significant effect on fat mass. [2]
9. No effect/non-significant effect on induction of aromatase and increase in estrogen. [2]
10. No effect/non-significant effect on power output increase. [2]
11. No effect/non-significant effect on weight. [2]
Conclusion
DAA may increase the testosterone levels, but the effect is small and not reliable. Increase in infertility is a more notable effect of DAA supplementation.
Verdict: Not needed in your supplement stackRecommended Dosage (Used in the Studies)
1. Cycling protocol (12 days on followed by a week without supplementation): 3,000mg/daily
2. Non-cycling protocol: 2,000mg daily
Where Can You Buy This Supplement?
Amazon.com
Side Effects of This Supplement
1. Continual supplementation with DAA (2,000mg daily) over 90 days did not show any harmfull effects. [2]
References
1. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats
2. d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men
| © Muscular Science 2013 |
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